Tuesday, 30 May 2023

3 Important things to know about High Speed Cooling Centrifuge

 

Utilizing the centrifugal force removes particles from water that range in mass and density. In this post, we will talk about the three key components of a high-speed cooling centrifuge. Learn how a high speed cooling centrifuge functions.

There are appealing qualities to the high speed cooling centrifuge. Its attributes include compact size, low weight, practical usage, simple controls, and automated working time management. A high speed cooling centrifuge's primary purpose is to isolate the necessary component from any liquid combination. Less dense liquid floats on top of the layer, whereas thick liquid settles to the bottom. In order to achieve the desired purity, the liquid will be layered.

1.       What is the purpose of a high-speed cooling centrifuge?

It is mostly used in scientific disciplines including biochemistry, genetic engineering, agriculture, forestry, food safety, and hospital medicine, among others. It allows for the fast separation of micro samples from one another and their use in synthesizing?

2.       What is the principle of cooling centrifuge?

Working Principles

A container containing two or more liquids is rotated in the centrifuging process so that the liquid with the lowest density rises to the top. It is occasionally necessary to centrifuge samples in a refrigerator to preserve sample integrity.

The fundamental principle underlying the creation of cool has a characteristic that causes the refrigerant to change from a liquid to a gas, resulting in a decrease in temperature. When the cooling system is first turned on, heat is reduced using the evaporator.

3.       Which type of centrifuge is the best?

Ultracentrifuges are centrifuges that operate at very high speeds. In specialized labs or in a research setting, they are typically utilized for sophisticated analysis. They rotate at a rate of 50,000 to 100,000 rpm.

Working principals of High Speed Cooling Centrifuge in Brief

·         Centrifugation Principle  Particles in a solution that have a density greater than the solvent's sink (are called sediment), while those that have a density lower than the solvent float to the top.

·         They move more quickly when the density difference is bigger. The particles remain stationary in isopycnic circumstances, when there is no density difference. 

·         Instead of using gravity, a centrifuge's significantly stronger "centrifugal force" may be used to separate different particles in a solution by taking advantage of even minute changes in density.

·         A centrifuge is a piece of machinery that spins an item in a circle around a fixed axis while providing a force that may be rather powerful perpendicular to the spin axis (outward).

·         Less dense things travel to the centre and are dispersed at the same time.

·         The centrifuge operates according to the sedimentation principle, in which denser materials and particles migrate outward in a radial direction as a result of centripetal acceleration.

·         Denser particles fall to the bottom of sample tubes used in laboratory centrifuges, whereas lighter materials rise to the top due to radial acceleration.

Connect with IGene Labserve by visiting https://www.igenels.com/  or calling us at 09310696848 to learn more about the operation of a high speed cooling centrifuge. The high speed centrifuge must be stopped immediately and cannot be made to run if there is any irregularity, which is a crucial point to remember. The centrifuge machine may become damaged if the machinery is forced to run.

Tuesday, 23 May 2023

What is the advantage of stability chamber?

 

The stability chamber is a controlled environment that is designed to provide optimal and consistent temperature, humidity, and lighting conditions, making it ideal for storing and testing various products and materials. The advantages of stability chambers include:

1.       Preservation of Product Quality: Stability chambers maintain the quality of products by providing consistent, controlled environmental conditions that keep them safe from contamination, degradation, and other damaging factors. Companies can use stability chambers to evaluate the shelf-life of a product safely, without having to send it out for testing.

2. Accurate Testing: Stability testing helps to ensure that products maintain their quality throughout their lifecycle. This is particularly important in industries such as pharmaceuticals, cosmetics, and food and beverage, where product stability plays a critical role in regulatory compliance. The stability chambers ensure that products don't deteriorate quickly, helping to ensure that the test results are accurate and reliable.

3. Time and Cost Savings: Stability chamber save time and money by providing equipment that can perform controlled testing in a few days or weeks. Companies can quickly identify issues with the product or material compatibility before conducting more extended and expensive trials. By identifying issues early and addressing them, companies can save a lot of time and money in the long run.

4. Regulatory Compliance: Stability testing is a vital part of regulatory compliance in many industries. By using stability chambers, companies can ensure that their products meet the regulatory guidelines of bodies such as the FDA, WHO, or ISO. Stability testing helps to ensure that products are safe and that the manufacturers comply with regulations, preventing the risk of microbial contamination or chemical degradation.

In summary, stability chambers provide a controlled environment where products can be safely stored and tested for a variety of variables, including temperature, humidity, and lighting. With stability chambers, companies can maintain product quality, conduct accurate testing, save time and costs, and meet regulatory compliance requirements.

Saturday, 13 May 2023

Biological Safety Cabinet (BSC): How it Works to Protect You

 

A Biosafety Cabinet (BSC) is an engineering measure designed to shield lab personnel, the surrounding area, and work items from contact with infectious or biohazardous aerosols and splashes. When handling infectious agent-containing materials including initial cultures, stocks, and diagnostic specimens, aerosols and splashes of this nature may be produced.

The three States of Protection

ü  Personal defense against dangerous substances within the cabinet

ü  To prevent sample contamination, and use product protection.

ü  Environmental protection against the cabinet's internal pollutants.

Based on its ability to confine biological agents when handling them, biological safety cabinets are divided into three types.


Class I Biological safety cabinet

As unsterile room air is pulled over the work surface, the Class I BSC is the first and most basic biological safety cabinet (BSC) that protects people and the environment but not the creation of products. Work with biological material in Risk Groups 1, 2, and 3 (RG1, RG2, and RG3, respectively) is appropriate for Class I BSCs.

How it works?

ü  Provides you with personnel, product and environment protection

ü  It is utilized while working with low to moderate risk biological agent

ü  Biosafety Levels: 1, 2 and 3

 

Class II Biological Safety Cabinet (BSC)

It is commonly found in clinical and research laboratories working with infectious agents in Risk Groups 2, 3, and 4 (if positive-pressure suits are used) or with tissue culture.

How it works?

ü  Provides you with personnel, product and environment protection

ü  It is utilized while working with low to moderate risk biological agent

ü  Biosafety Levels: 1, 2 and 3

 

Class III Biological Safety Cabinet (BSC)

Risk Group 4 agents employ Class III BSC, which offers the maximum level of personnel safety. It is acceptable for use in laboratories with Biosafety Levels 3 and 4.

How it works?

The maximum level of protection for the environment, the product, and the user is provided by a Class 3 cabinet, which offers the same protection as a Class 2 but is made for working with highly contagious substances classified as Biosafety Level 4.

It is mostly used when handling biological substances that carry an extremely high risk of harm.

To guarantee that no particles may seep out into the space, this sort of cabinet is completely sealed and pressure tested. Two HEPA filters separate the exhaust air from the supply air before it is released into the environment.  The operator uses thick rubber gloves that are a component of the Biosafety Cabinet to reach the work area. The work surface may be extended by connecting several glove boxes together.

Visit https://www.igenels.com/  or call 09310696848 to get in touch with IGene Labserve if you want to get a high-quality Biosafety Cabinet and learn all there is to know about the item.

How to Effectively Use the Water Bath in the Laboratory for Optimal Results?

  A shaking water bath is used for mixing and agitating samples in a water bath under controlled temperature. Compared to other types of ...