Tuesday, 27 December 2022

3 Operating rules for High Speed Cooling Centrifuge

This device is mostly used in laboratories; it uses centrifugal force to separate particles of various mass or densities immersed in a liquid. We would like to discuss some of the operating rules for high speed cooling centrifuge for your convenience in the long run.

The high speed centrifuge has the qualities of attractive appearance, small size, light weight, automatic working time management, straightforward operation, and practical usage. The primary function of the high speed cooling centrifuge is to separate the necessary components from the liquid mixture. The less dense liquid floats on the top layer after being adjusted and rotated, while the denser liquid sinks on the bottom layer according to each substance's density. The liquid will be layered in order to obtain the necessary purity.

The tool is one of the essential pieces of equipment used in the pharmaceutical sector. The high speed centrifuge is a product of choice for cell culture separation, molecular biology, and clinical medicine and is a fairly frequent piece of equipment in the contemporary centrifugal area. The versatility and processing power of centrifuge machines now meet new criteria.

We must begin from several aspects in order to preserve the high speed centrifuge's strong performance:

  • Before using the high speed centrifuge, read the instructions carefully, abide by the suggested usage procedures, make sure the machine is supplied with the proper mixture of water and air, and do the necessary proportioning. The lubricating oil used must be of an approved brand and be regularly inspected.
  • We need to keep a close eye on the centrifuge apparatus as well as the temperature of the bearing and the equipment's vibration process. Inspect the equipment periodically for leaks and strange noises, and deal with them right once if you find them. Always maintain a clean working environment. Do not place the components on the ground immediately. You must begin to form good operating habits now so that you may prevent the blunders of bad operation.
  • For repair and maintenance, it is essential to utilise the accessories that the original equipment manufacturer supplied. The accessories should be kept in a spot that is tidy, secure, and dry. To maintain the performance and dependability promised and the equipment's service life, it is imperative to exclusively utilise original accessories.

When using the device, you must pay attention to the operating principle. You must start with routine maintenance and proper use in order to operate it safely. The high speed centrifuge must be used correctly in order to adhere to the rules that need to be followed in order to increase the machine's productivity.

We can keep the high speed centrifuge's strong running ability, particularly if it is utilized appropriately in accordance with its specifications.

If you want to learn everything there is to know about a high-quality high-speed cooling centrifuge, get in touch with IGene Labserve by going to https://www.igenels.com/  or calling 09310696848. The crucial thing to remember is that the high speed centrifuge must be promptly stopped and cannot be pushed to run if there is any anomaly; otherwise, the centrifuge machine may be harmed.

Thursday, 8 December 2022

Uses of Ultra Low-Temperature Freezer

 

Hospitals
Blood banks and transfusion centers
Microbiological research institutes
Chemical research laboratories
Pharmaceutical research laboratories
Industrial research laboratories (food, textile materials)
Medical research institutes (genetics, prevention of diseases, and epidemics)

Monday, 5 December 2022

Do You Know the Types of Biosafety Levels?

Researchers have to focus on safety levels while working with autoclaving equipment in a laboratory setting. To ensure the safety of scientists and lab technicians, the regulatory bodies have defined biosafety cabinet levels---each with particular safety protocols---for various types of facilities. Biological Safety Levels (BSL) can be referred to as a series of protections pertaining to autoclave-related activities that take place in biological labs. Biosafety levels are ranked from one to four based on the organisms laboratory personnel are experimenting on.

How are biosafety levels defined?

The purpose of setting biosafety levels is to indicate what particular measures a laboratory must have in place for the containment of biological agents and microbes. Each biosafety level is defined according to the following factors:

  1. Risks associated with containment
  2. Transmissibility
  3. Severity of infection
  4. Origin of the microbe
  5. Type of the work conducted in the lab
  6. Route of exposure
  7. Agent in question

Types of biosafety levels

Given below are the 4 types of biosafety cabinet levels:

  1. Biosafety level 1 (BSL-1): Considered to be the lowest of the four biosafety levels, BSL-1 applies to laboratory settings in which researchers work with low-risk contaminants that have little to no threat of infection in adults. For instance, a BSL-1 laboratory may work with a nonpathogenic strain of E. coli. These labs conduct research on benches, and hence, don’t use any kind of special containment equipment. Safety protocols for BSL-1 labs include mechanical pipetting, regular handwashing, safe sharps handling, biohazard signs, etc.
  2. Biosafety level 2 (BSL-2): BSL-2 covers laboratories that work with agents related to human diseases. More often, these agents come in the form of infectious or pathogenic organisms that pose a moderate health hazard. Such agents include equine encephalitis viruses, staphylococcus aureus, and HIV. These biosafety cabinet labs adhere to the standard microbial practices as BSL-1 labs coupled with enhanced measures owing to the potential risks associated with these microbes. Researchers working in BSL-2 labs are expected to take extra precautions to prevent injuries like cuts, bruises, and other skin breakages. The safety protocols established for BSL-2 labs include the use of PPE, self-closing doors, and access to a sink. However, access to a BSL-2 lab is more restrictive than a BSL-1 lab.
  3. Biosafety level 3 (BSL-3): A BSL-3 lab works on indigenous microbes that can cause serious disease through inhalation. In BSL-3 labs, common examples of microbes include the West Nile virus, yellow fever, and tuberculosis bacteria. Contaminants found with BSL-3 settings are strictly controlled through regulatory bodies. Here, the researchers are also under medical surveillance and may require immunizations to combat the impact of microbes. The safety control measures within a BSL-3 lab include the use of PPE, solid-front wraparound gowns, and scrub suits, access to an eyewash station, sustained directional airflow, and a self-closing set of locking doors.
  4. Biosafety level 4 (BSL-4): BSL-4 labs are rare as they work with exotic and highly dangerous microbes like Marburg and Ebola viruses. These microbes create fatal infections and come without treatment. The safety protocols to be followed in BSL-4 labs include decontamination of materials and wearing the PPE from lower BSL levels apart from level 3 considerations. It’s one of the reasons why these labs are isolated and located in a separate building entirely. These biosafety cabinet labs also feature a supply of exhaust air, as well as decontamination systems and vacuum lines.

A biosafety level is a set of biocontainment precautions required to isolate hazardous biological agents in a closed laboratory facility. Before working with microbes in a lab setting, you need to know the difference between corresponding safety requirements and biosafety levels.

How to Effectively Use the Water Bath in the Laboratory for Optimal Results?

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