Thursday, 28 April 2022

Different Components of Gel Documentation System

 

 

Gel documentation systems are used largely in molecular biology labs to image and record nucleic acids and proteins suspended on agarose or polyacrylamide gels stained with fluorophores such as SYBR green or ethidium bromide.
Source of Irradiation
Visible Light
Base Plate
Hood
Filter
Adjustable Stage
Readout System
Imaging System

Monday, 25 April 2022

Do You Know the Three Classes of Biosafety Cabinets?

 

Researchers use biosafety cabinet to protect themselves from harmful chemicals during experimentation. It preserves the exact quality of the sample being tested by filtering out the inflow and exhaust air. Biosafety cabinets come in several designs and provide various levels of protection to the investigator and the research material. So, let’s explore the three classes of biosafety cabinets:

Class 1 cabinet

This ventilated cabinet provides protection to the personnel and environment from hazardous laboratory substances. Every accessory comes with a constraint, and a class 1 cabinet isn’t an exception in this regard. Their airflow pattern is similar to a fume hood with a HEPA filter at the exhaust outlet. Being the most basic biosafety cabinet, class 1 cabinets are used to enclose certain equipment like centrifuges. The cabinets of this class can either be ducted or not ducted.

Class 2 cabinet

Biosafety Class 2 cabinets have a fan mounted at the top that emits sterile air over the experiment area. The makeup air of a class 2 cabinet is also HEPA-filtered like the class 1 cabinet type. Class 2 cabinets are further divided into five types based on their embedded mechanism and exhaust system type:

  1. Type A1: These cabinets have an inflow velocity of 75ft/min.

  2. Type A2: A2 cabinets come with an inflow velocity of 100 ft/min.

  3. Type B1: B1 cabinets use single-pass airflow to curb the emission of hazardous gases.

  4. Type B2: Here, the air is drawn from an opening that is positioned at the top of the cabinet.

  5. Type C1: C1 cabinets function by implementing the single-pass airflow system. In this type, the cabinets shuffle the air by blending it with the downflow air.

Class 3 cabinet

Class 3 ventilated cabinets are leak-tight, unlike class 1 and 2 cabinets. Here, the air enters or leaves through a HEPA filter. Class 3 biosafety cabinet have rubber gloves attached to the system that is used during cabinet operations. One unique feature of this cabinet is that it has a transfer chamber that sterilizes the materials in the glove box. The gloves don’t allow contact between the samples and the operator. Biosafety class 3 cabinets are used in particular laboratories where the lab equipment is manufactured inside the chamber. With all these designs and structural features, maximum protection is guaranteed to the sample, the operator, and the environment.

As you can understand, these cabinets are extremely useful in research labs as they offer optimum protection to the investigator, sample, and environment. Not everyone can use these cabinets as they have a specific way of functioning. Undoubtedly, these high-end accessories have simplified the work of researchers in more ways than one.

Are you looking for the best biosafety cabinet to meet your research needs? If you feel so, then www.igenels.com has all the answers for you. In this platform, you get access to a wide variety of lab equipment and accessories at competitive rates. So, why think? Buy the one that fits your requirements.

Monday, 11 April 2022

BIOSAFETY CABINET USE AND SAFETY

 


Personal Protection from harmful agents within the cabinet
Product Protection to avoid contamination of the samples.
Environmental Protection from contaminants contained within the cabinet.

Monday, 4 April 2022

How many stability chambers are there?

The stability chamber are used to study the impact of pre-specified circumstances on life-saving pharmaceuticals, biological samples, electronic components, and industrial parts, among other things. Before getting into the different types of stability chambers, let’s find out about a few important features of this product.

Important features and models of stability chambers

  • Construction: A robust stainless steel frame supports the entire stability chamber. The stainless steel is thick gauge 304 or 316. Between the inner and outer chambers, high-density PUF insulation is used. Each chamber has a sufficient number of steel wire mesh cable trays (removable), ranging from 4 to 8 or more.
  • Refrigeration System: The stability chambers are equipped with branded CFC-free compressors that are hermetically sealed and operate quietly.
  • Temperature & Humidity: The stability test chambers include a temperature range of 10°C to 60°C and a humidity range of 35 percent to 95 percent relative humidity. Our chambers are appropriate for storage settings of 25°C at 60% RH, 40°C at 75% RH, 30°C at 65% RH, and 25°C at 40% RH, according to ICH recommendations.
  • Safety Features: Each stability chamber has several safety features to ensure that you are working with reliable equipment. Over-temperature protection, over current protection, low and high-temperature restrictions, as well as a time delay for compressor start-up, are all included in each chamber.
  • Air circulation: Because air circulation is required to maintain a consistent temperature and humidity throughout the chamber, we equip our stability test chambers with a motorized blower assembly that operates quietly and has a long service life.

Six Sizes of Stability Chambers   

Model                         Volume

IGL-SC200                 200 Liters

IGL-SC324                 324 Liters

IGL-SC450                 450 Liters

IGL-SC600                 600 Liters

IGL-SC800                 800 Liters

IGL-SC1000               1000 Liters

IGene Labserve offers some of the best quality stability chambers, various optional changes can be made in this product over suggestions like:

- Stainless steel exterior (GMP)

- RS 485 interface

- PLC based HMI controller w/ USB interface

- 21 CFR part 11software

- Storage racks

- UV light

If there is anything you are looking to understand about stability chambers, then visit their official website at https://www.igenels.com or dial 09310696848 to speak to them directly.

How to Effectively Use the Water Bath in the Laboratory for Optimal Results?

  A shaking water bath is used for mixing and agitating samples in a water bath under controlled temperature. Compared to other types of ...